User Control can access only within the current application,if u want to access the user control to other application,u want to copy that user control to that application. Custom control can access from any application becs it is stored in GAC(Global Assembly Cache). We can add the custom control to Visual studio IDE toolbox,but user control can't. User control is good for static layout Custom control is good for dynamic layout. User Control will appear in the Solution Explorer where as custom control will appear in the toolbox, the significant of both controls is re-usability.User control will use with in the application where as Custom Control will use in any application because it is in the tool box. Extending the functionality of the existing control is Custom Control and grouping up of existing controls for desired out put is user control.
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